CICU and Chronic Inflammatory Demyelinating Polyneuropathy

Of the other benzodiazepines used Everyday sleep disorders flunitrazepam (Rohypnol), diazepam (seduksen), midazolam (dormikum), estazolam, flurazepam, Temazepam, triazolam. In small doses, sedative hypnotics (calming) effect. Benzodiazepines - a large group of substances, preparations which used as a hypnotic, anxiolytic, antiepileptic, muscle relaxant funds. Nitrazepam (radedorm, eunoktin) appointed interior for 30-40 minutes before sleep. Nebenzodiazepinovye stimulants benzodiazepine receptor zolpidem (ivadal) and zopiclone (imovan) have little effect on sleep structure, do not have pronounced muscle relaxant and anticonvulsant action, not cause withdrawal symptoms and therefore a better tolerability profile. In these cases, intravenous specific benzodiazepine receptor antagonist flumazenil. In connection with the action of benzodiazepines myshechnorasslablyayuschim contraindicated in myasthenia gravis. From blockers H1retseptorov just as hypnotic use doxylamine (donormil) - preparation, virtually no influences the sleep pattern. The mechanism of hypnotic action is associated with potentiation inhibitory action of GABA. These compounds stimulate the membranes direction-finder neurons of the CNS benzodiazepine receptors, which are allosterically linked to GAMKAretseptorami. Under the action of GABA opens Cl channels and hyperpolarization of here membrane develops neuron. Melatonin - a synthetic analogue of the hormone of pineal gland involved in the provision of circadian rhythms change of wakefulness and sleep. Typically, acetaldehyde is rapidly oxidized ацетальдегиддегидрогеназой. The drug reduces the excessive reaction to outside stimuli, contributes to onset of sleep and provides sleep for 6-8 hours when the systematic application of nitrazepama may show its side effects: lethargy, sleepiness, decreased alertness, slowed reactions, possible diplopia, nystagmus, itching, rash. direction-finder a result, only one type of or the smell of alcohol causes in patients nausea and vomiting. Barbiturates - High-hypnotics, and help sleep onset, warn frequent waking, increase total sleep time. Assign a long time after treatment for alcoholism. In large doses, these substances are able to provide narcotic effect. Benzodiazepines for insomnia help sleep onset, increase its duration. However, this several changes of sleep Quality and Outcomes Framework it decreases the duration REMfaz sleep (REM sleep, REM sleep: periods of 20-25 mines, which are repeated during sleep several times, accompanied by dreams and rapid movements of the eyeballs - Rapid Eye Movements). Akamprozat - GABA receptor agonist reduces craving for alcohol. Disulfiram inhibits atsetaldegiddegidrogenazu and retards the oxidation of ethanol to acetaldehyde stage. direction-finder certain days of treatment patients receive small amounts of alcohol (40-50 ml of vodka). Patients strongly warns against, the dangers of drinking alcohol during the period of preparation. A similar principle is used in the treatment of alcoholism, using Disulfiram (Teturi, Antabuse). Thus, benzodiazepines reinforce the processes of inhibition in the CNS. Under the action of benzodiazepines increases the frequency of opening S1kanalov.