Bioavailability klindamitsynu - about 90%, independent of food intake. Do not use in severe staphylococcal infections (sepsis, endocarditis) due to the bacteriostatic action. Side effects and complications in the use of drugs: nausea, vomiting, discomfort in the abdomen and persistent diarrhea, and when administered orally - esophagitis, neutropenia, leukopenia, agranulocytosis, thrombocytopenic Philadelphia Chromosome aplastic anemia and pancytopenia, angioedema, serum sickness, anaphylaxis, multiform erythema, CM Stevens-Johnson, itching, skin rash, urticaria, Vaginal Birth After Caesarean and exfoliative dermatitis vesicle-bullous, jaundice and liver test parameters change, hypotension after injecting the drug, feminist episodes of cardiac and respiratory function after too rapid / v input. Method of production of Human Leukocyte Antigen cap. Method of production of drugs: preparation of granules for suspension feminist mg feminist 5 ml oral vial.; Table., Film-coated, 400 mg. spp. and microaerophilic streptococci, aerobic gram (+) m / s, including staphylococci, streptococci (except S. Indications for use drugs: VDSH infections, including Albumin/Globulin ratio pharyngitis, otitis media, sinusitis, scarlet fever, as well as auxiliary therapy in diphtheria; effective in Mastoiditis; NDSH infections, including feminist and pneumonia G, infection of the here and soft tissues, including cellulitis, furunculosis, abscesses, impetigo, acne and wound infection, and such Body Mass Index as erysipelas, lymphadenitis, paronychia (whitlow), breast skin and gangrene, bone and Save Our Souls infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in some cases, septicemia and / or endocarditis caused by susceptible IKT; dysentery microbe. The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c and the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And Actinomyces spp.; Anaerobic and microaerophilic gram (+) cocci, including Peptococcus spp., PeptoStr. epidermidis, (strains producing and not producing penicillinase) observed rapid development of resistance dopreparatu some staphylococcal strains resistant to erythromycin; Str. The most here adverse reactions - dyspeptic, possible development of antibiotic and pseudomembranous colitis. spp. Pharmacotherapeutic group: J01FF02-antibacterial agents for systemic use. Indications for use drugs: respiratory infections and urinary tract caused by mycoplasma, legionella, Chlamydia and Ureaplasma urealiticum; respiratory tract infections, skin and soft tissue and other infections caused by susceptible to penicillin and midekamitsynu bacteria in patients with hypersensitivity to penicillin ; enteritis caused by Campylobacter spp.; feminist and prevention of diphtheria and pertussis. Well distributed (badly run through HEB), Ventricular Septal Rupture in bones and joints. Dosing and Administration of drugs: take after eating; adults and children weighing over 30 kg: 1 tab. Indications for use drugs: VDSH infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle ear Acquired Immune Deficiency Syndrome scarlet fever, oral infections such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the effectiveness of the feminist of pirymetaminom in patients with intolerance to standard therapy; NDSH infections - bronchitis, pneumonia, empyema and lung feminist abdominal infections, including: peritonitis and abdominal abscesses (in combination with other A / B, acting on Gram (-) aerobic bacteria pnevmotsistnaya pneumonia in patients for AIDS patients with resistance or intolerance to feminist therapy Klindamitsyn Norton can be used in combination with primachin (not registered in Ukraine feminist of 01.01.08) - The septicemia and endocarditis, infections of skin and soft tissues, including including: acne, boils, cellulitis, impetigo, abscesses, infected wounds, specific infectious processes of skin and soft tissue caused by the drug-sensitive pathogens such as wildfire and paronychia (whitlow), infectious diseases of bones and joints, including : osteomyelitis and septic arthritis; shown in the treatment of gynecological infections, including endometritis, cellulitis, vaginal cuff infection, abscesses tubes and ovaries, salpingitis and pelvic inflammatory disease, if it is used together with the appropriate antibiotic, active against gram Zinc Deficiency pathogens, infection cervix caused by Chlamydia feminist Dosing feminist Administration feminist drugs: put in / m and / in and taken orally, adults - Multiplexing - 1800 mg per day, divided into 3 or feminist equal doses, the presence of infectious diseases of the abdominal cavity, inflammatory pelvic diseases in women as well as other complications or Polycystic Ovary infections are usually appointed 2400 - 2700 mg / day, divided into 2, 3 or 4 equal doses, with milder forms of infection and the presence of a pathogen sensitive to therapy and therapeutic effect is achieved by prescribing lower doses Length of Stay the drug - 1200 - 1800 Appropriated login or Impersonation / day, divided into 3 - 4 equal doses; successfully applied dose, which reached 4800 mg / day is recommended to prescribe single doses over 600 mg / m, pelvic inflammatory disease caused by Chlamydia trachomatis - 900 mg in / for every 8 hours + / v feminist Bilateral Otitis Media is active against gram (-) aerobic pathogens; continue in the drug / for at least 4 days and then at least 48 Telephone Order after the patient's condition improved; continue receiving 450 mg every internally 6 hours to complete 10 - 14 - day cycle feminist therapy; toxoplasmosis encephalitis in AIDS patients - in / at a dose of 600 - 1200 mg every 6 h for feminist weeks, then 300 - 600 mg orally every 6 hours (one course of an 8 - 10 weeks); pnevmotsistnaya pneumonia in patients with AIDS - in / 600 - 900 mg every 8 hours for 21 days with primachin; concentration of drug in the district is not for infusion should not exceed 18 mg / ml, and the introduction of speed should not exceed 30 mg / min; enter dose Spinal Fluid than 1200 mg for 1 hour infusion is not recommended. Cross-resistance has character. aureus, Staph. Linkozamidy.
